https://doi.org/10.4081/ripppo.2020.464
After more than sixty years we are still unclear whether LSD has a place in clinical psychiatry
Submitted: May 18, 2020
Accepted: July 6, 2020
Published: October 1, 2020
Accepted: July 6, 2020
Abstract Views: 908
PDF: 526
HTML: 170
HTML: 170
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Dear Editor, The use of the psychedelic Lysergic Acid Diethylamide (LSD) has again provoked scientific debate over its efficacy and safety. In the 1950s-1960s LSD was used in psychotherapy for treating depression, anxiety related to terminal cancer, addiction, and pain. (...)
Bonson, K. (1996). Chronic administration of serotonergic antidepressants attenuates the subjective effects of LSD in humans. Neuropsychopharmacology, 14, 425-436.
DOI: https://doi.org/10.1016/0893-133X(95)00145-4
Carhart-Harris, R.L., and Goodwin, G.M. (2017). The therapeutic potential of psychedelic drugs: past, present, and future. Neuropsychopharmacology 42, 2105–2113;
DOI: https://doi.org/10.1038/npp.2017.84
Carhart-Harris, R.L., Bolstridge, M., & Rucker. J., et al. (2016). Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study. Lancet Psychiatry, 3(7), 619-27.
DOI: https://doi.org/10.1016/S2215-0366(16)30065-7
Fuentes, J.J., Fonseca, F., Elices, M., Farré., M., & Torrens, M. (2020) Therapeutic Use of LSD in Psychiatry: A Systematic Review of Randomized-Controlled Clinical Trials. Front. Psychiatry, 10, 943.
Gasser, P., Kirchner, K., and Passie, T. (2015). LSD-assisted psychotherapy for anxiety associated with a life-threatening disease: a qualitative study of acute and sustained subjective effects. Journal of Psychopharmacology, 29(1), 57–68.
DOI: https://doi.org/10.1177/0269881114555249
Mithoefer, M.C., Wagner, T.M., Mithoefer, A.T., Jerome, L., & Doblin, R. (2011). The safety and efficacy of ±3,4-methylenedioxymethamphetamine-assisted psychotherapy in subjects with chronic, treatment-resistant posttraumatic stress disorder: the first randomized controlled pilot study. Journal of Psychopharmacology, 25(4), 439-452.
DOI: https://doi.org/10.1177/0269881110378371
Mithoefer, M.C., Mithoefer, A.T., Feduccia. L., et al. (2018). MDMA-assisted psychotherapy for post-traumatic stress disorder in military veterans, firefighters, and police officers: a randomised, double-blind, dose-response, phase 2 clinical trial. Lancet Psychiatry, 55(6), 486-497.
DOI: https://doi.org/10.1016/S2215-0366(18)30135-4
Nutt, D. (2019). Psychedelic drugs—a new era in psychiatry? Dialogues in Clinical Neuroscience, 21(2), 139-147.
DOI: https://doi.org/10.31887/DCNS.2019.21.2/dnutt
Tupper, K.W., Wood, E., Yensen, R., & Johnson, M.W. (2015). Psychedelic medicine: a re-emerging therapeutic paradigm. CMAJ, 187(14), 1054-1059.
DOI: https://doi.org/10.1503/cmaj.141124
Ungerleider, J.T., & Adrysiak, T. (1981). Therapeutic uses of the drugs of abuse. Annals of the New York Academy of Sciences, 362, 173-180.
DOI: https://doi.org/10.1111/j.1749-6632.1981.tb12805.x
How to Cite
Saniotis, A. (2020). After more than sixty years we are still unclear whether LSD has a place in clinical psychiatry. Research in Psychotherapy: Psychopathology, Process and Outcome, 23(2). https://doi.org/10.4081/ripppo.2020.464
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Elham Qanbari Alaee, Omid Saed, Sahel Khakpoor, Reza Ahmadi, Mahsa Ali Mohammadi, Majid Yoosefi Afrashteh, Zekrolah Morovati, The efficacy of transdiagnostic cognitive behavioural therapy on reducing negative affect, anxiety sensitivity and improving perceived control in children with emotional disorders - a randomized controlled trial , Research in Psychotherapy: Psychopathology, Process and Outcome: Vol. 25 No. 1 (2022)
- Gloria Fioravanti, Martina Nicolis, Angus MacBeth, Giancarlo Dimaggio, Raffaele Popolo, Metacognitive interpersonal therapy-eating disorders versus cognitive behavioral therapy for eating disorders for non-underweight adults with eating disorders: study protocol for a pilot pre-registered randomized controlled trial , Research in Psychotherapy: Psychopathology, Process and Outcome: Vol. 26 No. 2 (2023)
- Osmano Oasi, Laura Buonarrivo, Alberto Codazzi, Margherita Passalacqua, Gio Matteo Risso Ricci, Francesca Straccamore, Roberto Bezzi, Assessing personality change with Blatt's anaclitic and introjective configurations and Shedler-Westen Assessment Procedure profiles: two case studies in psychodynamic treatment , Research in Psychotherapy: Psychopathology, Process and Outcome: Vol. 20 No. 1 (2017)
- Gaia Albano, Arianna Teti, Arianna Scrò, Rubinia Celeste Bonfanti, Lucia Fortunato, Gianluca Lo Coco, A systematic review on the role of therapist characteristics in the treatment of eating disorders , Research in Psychotherapy: Psychopathology, Process and Outcome: Vol. 27 No. 2 (2024)
- Annalisa Tanzilli, Flavia Fiorentino, Marianna Liotti, Gabriele Lo Buglio, Ivan Gualco, Vittorio Lingiardi, Carla Sharp, Riccardo Williams , Patient personality and therapist responses in the psychotherapy of adolescents with depressive disorders: toward the Psychodynamic Diagnostic Manual - third edition , Research in Psychotherapy: Psychopathology, Process and Outcome: Vol. 27 No. 1 (2024)
- Immacolata Zarrella, Luigi Alessandro Russolillo, Giorgio Caviglia, Raffaella Perrella, Continuity and discontinuity between psychopathology of childhood and adulthood: a review on retrospective and prospective studies , Research in Psychotherapy: Psychopathology, Process and Outcome: Vol. 20 No. 2 (2017)
- Christopher B. Harte, Raymond C. Hawkins II, Impact of personality disorder comorbidity on cognitive-behavioral therapy outcome for mood and anxiety disorders: results from a university training clinic , Research in Psychotherapy: Psychopathology, Process and Outcome: Vol. 19 No. 2 (2016)
- Chiara Manfredi, Gabriele Caselli, Federica Pescini, Martina Rossi, Daniela Rebecchi, Giovanni Maria Ruggiero, Sandra Sassaroli, Parental criticism, self-criticism and their relation to depressive mood: an exploratory study among a non-clinical population , Research in Psychotherapy: Psychopathology, Process and Outcome: Vol. 19 No. 1 (2016): Special issue on Qualitative and Quantitative Research in Child and Adolescent Psychotherapy: part 2
- Claudia Capella, Loreto Rodríguez, Estrella Azócar, Ximena Lama, Lucía Núñez, Daniela Águila, Camila Gomez, Macarena Espeleta, Vania Vasquez, Psychotherapeutic change in children and adolescents who have been sexually abused: a model from participants’ perspectives , Research in Psychotherapy: Psychopathology, Process and Outcome: Vol. 25 No. 1 (2022)
- CV Vijayapriya, Rameshbabu Tamarana, Effectiveness of dialectical behavior therapy as a transdiagnostic treatment for improving cognitive functions: a systematic review , Research in Psychotherapy: Psychopathology, Process and Outcome: Vol. 26 No. 2 (2023)
You may also start an advanced similarity search for this article.
